The invention provides a compound which is useful as a pharmaceutical component, especially as an effective component of a pharmaceutical component for the prevention and / or treatment of VAP-1 related diseases.The inventors have made a detailed review of the compounds with VAP-1 blocking activity, and found that the compounds or salts of the invention show excellent VAP-1 blocking activity, which is useful for the prevention and / or treatment of VAP-1 related diseases, especially diabetic kidney disease or diabetic macular edema. Also, the invention relates to a pharmaceutical composition containing a compound of the invention or a salt thereof, and an excipient thereof, in particular to a pharmaceutical composition for the prevention and / or treatment of a VAP-1 related disease.本發明為提供一種作為醫藥組成物，特別作為VAP-1關連疾病的預防及/或治療用醫藥組成物之有效成分為有用的化合物。本發明者們對於具有VAP-1阻礙活性的化合物進行詳細檢討結果，發現本發明化合物或其鹽顯示優良VAP-1阻礙活性，對於VAP-1關連疾病，特別對於糖尿病性腎臟病或糖尿病性黃斑水腫之預防及/或治療上有用而完成本發明。又，本發明係關於含有本發明化合物或其鹽、及賦形劑的醫藥組成物，特別為關於使用於VAP-1關連疾病的預防及/或治療之醫藥組成物。
