David Brian Corry,Farrah Kheradmand,Preethi Gunaratne,Sumanth Polikepahad,Arash Olyie Naghavi
申请号:
US13319466
公开号:
US20130177624A1
申请日:
2010.05.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are methods for detecting an allergic lung disease that involve assessing the level of one or more microRNAs (miRNAs) in a biological sample, wherein the level of the one or more miRNAs in the biological sample compared to a reference level of the one or more miRNAs is indicative of allergic lung disease. Also disclosed are methods for the treatment or prevention of inflammatory or allergic lung disease that involve administration of a let-7 miRNA inhibitor as set forth herein, as well as biochips and kits that can be applied in the methods of the present invention.