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EGFR ANTIBODY-BASED COMBINATION THERAPY
专利权人:
发明人:
申请号:
EP15854690.3
公开号:
EP3223857A1
申请日:
2015.10.30
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
EGFR antibodies can be combined to enhance their anti-cancer effect. In the present invention, at least one of two naked antibodies in a combination is provided as an antibody drug conjugate (ADC) in which the antibody is coupled with a cytotoxin. Both antibodies also can be provided in ADC form. The result is improved activity, with the improvement being synergistic in many such antibody pairs.
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