CURRIE, MARK G.,MAHAJAN-MIKLOS, SHALINA,LI, JING SUN
申请号：
CA2529307
公开号：
CA2529307C
申请日:
2004.06.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Compositions and related methods for treating IBS and other gastrointestinaldisorders and conditions (e.g., gastrointestinal motility disorders,functional gastrointestinal disorders, gastroesophageal reflux disease (GERD),duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory boweldisease, functional heartburn, dyspepsia (including functional dyspepsia ornonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (orcolonic pseudoobstruction), and disorders and conditions associated withconstipation, e.g., constipation associated with use of opiate pain killers,post-surgical constipation, and constipation associated with neuropathicdisorders as well as other conditions and disorders are described. Thecompositions feature peptides that activate the guanylate cyclase C (GC-C)receptor.
