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Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid and administration thereof
专利权人:
Vertex Pharmaceuticals Incorporated
发明人:
Marinus Jacobus Verwijs,Rossitza Gueorguieva Alargova,Ritu Rohit Kaushik,Irina Nikolaevna Kadiyala,Christopher Young
申请号:
US14542396
公开号:
US09241934B2
申请日:
2014.11.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a diluent, a disintegrant, a surfactant, a binder, a glidant and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Methods for treating a patient in need thereof include administering an oral pharmaceutical formulation of Compound 1 to the patient.
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