Disclosed is a medical device wherein a surface lubricating layer and one of various polymer bases are fixed with each other firmly by a simpler technique. The medical device permanently exhibits excellent surface lubricity when in use. Specifically disclosed is a medical device (10) which has a lubricating surface when wet. The medical device (10) is characterized by comprising a base layer (1) at least the surface of which is composed of a polymer material, a compound (thiol compound) (2) which is supported by at least a part of the base layer (1) and has a plurality of thiol groups in each molecule, and a surface lubricating layer (3) which covers the thiol compound (2) and is composed of a hydrophilic polymer that has a reactive functional group. The medical device (10) is also characterized in that the thiol compound (2) is supported by (fixed to) the base layer (1) by irradiation of ionized gas plasma, and that the surface lubricating layer (3) is bonded to the base layer (1) by reacting the thiol compound (2) with the hydrophilic polymer that has a reactive functional group.