An apparatus for vascular modeling is disclosed. The apparatus receives medical images from an imaging device that include representations of a coronary vessel tree of a subject recorded at a different viewing angles. The apparatus determines, from a first of the medical images, a first centerline set and first vessel diameters for sample points along the first centerline set, and determines, from a second of the medical images, a second centerline set and second vessel diameters for sample points along the second centerline set. The apparatus determines a correspondence between the first centerline set and the second centerline set, and determines diameters for a combined centerline set based on the correspondence of sample points along the first and second centerline sets. The apparatus provides the combined centerline set for estimating blood flow resistance values of the coronary vessel tree of the subject to determine at least one potential stenosis.
