The present invention refers to a peptide of general formula (I) R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2, cosmetic compositions which comprises said peptide, method of preparation of said peptides and its use in the treatment and/or prevention of itching, inflammation, pain, diseases and/or disorders of the respiratory airways.本發明關於通式(I)R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2之胜肽、包含該胜肽之化妝組合物、該胜肽之製備方法及其在治療及/或預防呼吸氣道之搔癢、發炎、疼痛、疾病及/或病症之用途。