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BICYCLIC AMINES AS NOVEL JAK KINASE INHIBITORS
专利权人:
LEO Pharma A/S
发明人:
Daniel Rodriguez GREVE,Tue Heesgaard JEPSEN,Mogens LARSEN,Andreas RITZEN
申请号:
US16479375
公开号:
US20190382418A1
申请日:
2018.01.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to a compound according to formula Iwherein R1 represents alkyl; n is 1 or 2; R2 is selected from the group consisting of hydrogen, cyano, —;SO2Ra, —;SO2NRbRc, —;C(O)Rb, phenyl and 5- and 6-membered heteroaryl or pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention relates further to, to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.
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