AMADEO MARK PARISSENTI,BAOQING GUO,KENNETH PRITZKER,LAURA PRITZKER,MU ZHU,RASHMI NARENDRULA,STACEY SANTI,XIAOHUI WANG
申请号：
BR112014026440
公开号：
BR112014026440A2
申请日:
2013.04.24
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
abstract various embodiments are described herein related to an assay, method and apparatus for performing an rna disruption assay (rda) for cellular rna optionally in response to a cytotoxic treatment such as chemotherapy and / or radiation treatment. the method comprising obtaining at least one electropherogram dataset corresponding to a unique biological sample comprising the cellular rna at a time point, optionally during or after the treatment； determining values for features from at least two shifted regions of at least one electropherogram dataset, the shifting being due to the treatment； and optionally determining an rda score based on a combination of the values of the features. 1abstract various embodiments are described herein related to an assay, method and apparatus for performing an rna disruption assay (rda) for cellular rna optionally in response to a cytotoxic treatment such as chemotherapy and/or radiation treatment. the method comprises obtaining at least one electropherogram dataset corresponding to a unique biological sample comprising the cellular rna at a time point, optionally during or after the treatment； determining values for features from at least two shifted regions of the at least one electropherogram dataset, the shifting being due to the treatment； and optionally determining an rda score based on a combination of the values of the features. 1
