Talarazole metabolites

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专利权人:

Debra Barrett

发明人:

Debra Barrett

申请号：

US12311862

公开号：

US08188124B2

申请日:

2007.10.17

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Novel metabolites of talarazole of formula (I) have been isolated and characterized, wherein R═H, OH, OSO3H or O-gly； R1, ═H, OH, OSO3H, O-gly or =0； and gly=a glucuronate, or a pharmaceutically acceptable salt thereof. These compounds are targeted for the treatment of various skin-, hair- and nail-associated disorders.

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