THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
KADOCH, CIGALL,CRABTREE, GERALD R.
申请号：
CA3001000
公开号：
CA3001000A1
申请日:
2016.10.05
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Methods useful in the treatment of synovial sarcoma are provided. The methods comprise administering to a subject suffering from synovial sarcoma a compound as disclosed herein. Also provided are novel compounds having therapeutic effects on subjects suffering from synovial sarcoma and pharmaceutical compositions comprising the compounds. The compounds were identified by screening for agents that promote the assembly of wild-type BAF (also called mSWI/SNF) complexes in modified SS cells.
