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Heterocyclic-Fused Pyrazolo[4,3-c] Pyridin-3-One M1 Receptor Positive Allosteric Modulators
专利权人:
Douglas C. Beshore
发明人:
Douglas C. Beshore,Scott D. Kuduk
申请号:
US13395992
公开号:
US20120178760A1
申请日:
2010.09.20
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to heterocyclic fused pyrazole[4,3-c]pyridine-3-one compounds of formula (I): which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimers disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
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