A method of preparing a ready-to-use catheter, said method comprising: providing a catheter assembly (1,1',1'',1'''), comprising: a first compartment (2) comprising a catheter (3), said catheter (3) comprises on at least a part of its surface (6) an exterior coating (7) designed to reduce the coefficient of friction after treatment with a liquid swelling medium (5), and a second compartment (4) comprising the liquid swelling medium (5), said method further comprises sterilising the catheter assembly (1,1',1'',1'''), adding the liquid swelling medium (5) to the first compartment (2) for wetting/activating the catheters exterior coating (7), and storing the ready-to- use catheter. By using the method according to the invention, the sterilisation of the catheter is effectuated in a dry- state, ensuring that the known problems with wet-sterilisation are completely eliminated and the need for preparing complicated and expensive liquid swelling mediums are no longer a requirement.