A vascular prosthesis comprising a tubular shaped expandable ECM member and at least one anchoring mechanism. In one embodiment the anchoring mechanism comprises proximal and distal single or dual ring anchors. In one embodiment the anchoring mechanism comprises a multiple ring anchor. The anchors preferably comprise a biodegradable metal such as magnesium. The anchors can also comprise a shape memory alloy such as nitinol and a cross linked ECM material. In some embodiments the ECM member includes a pharmacological agent.
