Methods and apparatus for stabilizing vascular tissue adjacent the site of the placement of an intravascular repair vehicle such as a stent graft are provided. Thus, there is provided a method for stabilizing a segment of a blood vessel for placement of an intravascular repair vehicle comprising: isolating the segment of the blood vessel infusing the isolated segment with a sclerosing agent creating a sclerosed segment removing the sclerosing agent and deploying the intravascular repair vehicle at the sclerosed segment.