Anna De Fazio,Paul Robert Harnett,Alexander David Guminski
申请号：
US11793485
公开号：
US08673869B2
申请日:
2005.12.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides methods for determining the level of resistance of a tumor cell to one or more chemotherapeutic agents, comprising measuring the level of expression of a muscle ankyrin repeat protein in the tumor cell. The invention also provides methods for increasing the sensitivity of a tumor cell to one or more chemotherapeutic agents, comprising administering to the cell an effective amount of an antagonist of a muscle ankyrin repeat protein. The invention further provides compositions for use in accordance with methods of the invention.
