Thomas J. Webster,Godofredo R. Dimaano,Kevor Shane Tenhuisen,Gene Kulesha,John Muth
申请号：
US14570374
公开号：
US20160166391A1
申请日:
2014.12.15
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Methods of manufacturing produce metal implants having nano-modified surfaces that contain antimicrobial properties. The methods may include immersing the implant in an acid, rinsing the acid-treated implant in an aqueous cleaner, and thereafter heating the rinsed implant. The nano-modified implants described herein may contain an increased surface roughness surface features with increased width or height and/or decreased surface energy. The implants that result from these methods contain a nano-modified surface that is resistant to microbial cell adhesion and ultimately reduce biomaterials-related infections at the implant site.
