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Nucleic acids encoding chromophores/fluorophores and methods for using the same
专利权人:
Sergey A. Lukyanov
发明人:
Sergey A. Lukyanov,Arcady F. Fradkov,Yulii A. Labas,Mikhail V. Matz,Alexey Terskikh
申请号:
US11607828
公开号:
US09834584B2
申请日:
2006.11.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Nucleic acid compositions encoding chromo/fluoroproteins and mutants thereof, as well as the encoded proteins, are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein. Also of interest are proteins that are substantially similar to, or mutants of, the above specific proteins. Also provided are fragments of the nucleic acids and the peptides encoded thereby, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications, e.g., that include the subject nucleic acid compositions, are provided.
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