BHAKTA, Sunil,ERICKSON, Hans,JUNUTULA, Jagath R.,KOZAK, Katherine,OHRI, Rachana,PILLOW, Thomas
申请号：
HK18102603.5
公开号：
HK1243103A
申请日:
2018.02.23
申请国别(地区):
HK
年份:
2018
代理人:
摘要：
Cysteine engineered antibodies comprising a free a cysteine at position 140 according to EU numbering in the heavy chain are generated. These antibodies are prepared by mutagenizing a nucleic acid sequence of a parent antibody to introduce a A140C mutation； expressing the cysteine engineered antibody； and isolating it.
