1. To inhibit the formation of attachment after operation, target countries of H4 receptor selected from [5-(4,6-dimethyl-1H-benzodiazepine-2-IL) -4-methyl-pyridine-2-IL] - [3-(1-methyl-pyridine-4-IL) -propyl] were used.
The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering a histamine H4 receptor antagonist, systemically, directly to tissue surfaces in the body cavity, or both, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure. The drug is selected from the group consisting of benzoimidazol-2-yl pyrimidines and pyrazines.USO DE UN ANTAGONISTA DEL RECEPTOR H4 DE HISTAMINA SELECCIONADO DE [5-(4,6-DIMETIL-1H-BENZOIMIDAZOL-2-IL)-4-METIL-PIRIMIDIN-2-IL]-[3-(1-METIL-PIPERIDIN-4-IL)-PROPIL]-AMINA O UNA SAL FARMACÉUTICA ACEPTABLE DEL MISMO, PARA LA INHIBICION DE LA FORMACION DE ADHERENCIAS POSTOPERATORIAS.
