TRIEBEL, FREDERIC,VANHOVE, BERNARD,HAUDEBOURG, THOMAS
申请号:
CA2685584
公开号:
CA2685584C
申请日:
2008.04.30
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention concerns a molecule binding to LAG-3 protein and causing depletion of LAG-3 activated T cells particularly said molecule is a cytotoxic anti-LAG-3 monoclonal antibody or fragment thereof. It also concerns a method of treating or preventing organ transplant rejection or autoimmune diseases in a mammal comprising administering to said mammal a therapeutically effective amount of said antibody.