CHEONG SOK CHING,TEO SOO HWANG,LIM KUE PENG,MOHD ZAIN ROSNAH,ABDUL RAHMAN ZAINAL ARIFF,PONNIAH SATHIBALAN
申请号：
IN64/DELNP/2014
公开号：
IN2014DN00064A
申请日:
2014.01.03
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
THE PRESENT INVENTION RELATES TO A PEPTIDE COMPRISING AT LEAST AN AMINO ACID SEQUENCE SELECTED FROM AT LEAST A PORTION OF MAGE D4B PROTEIN WHICH THE PEPTIDE IS CAPABLE OF BINDING WITH AT LEAST A HUMAN LEUKOCYTE ANTIGEN (HLA) MOLECULE. THE BINDING OF THE PEPTIDE WITH THE HUMAN LEUKOCYTE ANTIGEN (HLA) MOLECULE DESCRIBED HEREIN IS CAPABLE OF INDUCING THE IMMUNE SYSTEM OF A SUBJECT TO RECOGNIZE ORAL CANCER CELLS AS BEING FOREIGN. UPON BEING RECOGNIZED AS FOREIGN PARTICLES THESE CELLS ARE TARGETED AND DESTROYED BY THE CD8CYTOTOXIC T CELLS. FURTHER DISCLOSED IN THE PRESENT INVENTION IS A CANCER VACCINE DERIVED FROM THE MAGE D4B PEPTIDES AND THE USE OF SAID CANCER VACCINE.
