Yoon Keun Kim;Bok Sil Hong;Yu Sun Kim;Eun Young Lee;Sung Wook Hong;Jun Pyo Choi;Young Koo Ji;Yong Song Gho;Eun Jeong Choi
发明人:
Yoon Keun Kim,Yong Song Gho,Yu Sun Kim,Eun Jeong Choi,Sung Wook Hong,Eun Young Lee,Bok Sil Hong,Jun Pyo Choi,Young Koo Ji
申请号：
US13499653
公开号：
US20120192295A1
申请日:
2010.08.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present application relates to a composition comprising extracellular membrane vesicles derived from indoor air. In addition, the present application provides a method for diagnosing, preventing and/or treating an inflammatory respiratory disease, lung cancer and the like using the extracellular membrane vesicles. In detail, the present application involves injecting extracellular membrane vesicles present in indoor air into an animal in order to prepare an animal respiratory disease model, and enables the search and/or discovery of drug candidates for preventing or treating respiratory diseases using the animal model. The present application provides a vaccine for preventing and/or treating respiratory diseases, to a method for diagnosing substances causing respiratory diseases, and to a method for inhibiting the activities of extracellular membrane vesicles in indoor air or removing the extracellular membrane vesicles from indoor air so as to prevent the occurrence and exacerbation of respiratory diseases.
