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Chewy composition for oral use and Process for preparing the same
专利权人:
SANOFI
发明人:
GEORGES DASTE,BENJAMIN DEROUET,MARIE RENOUARD
申请号:
ARP140100449
公开号:
AR094770A1
申请日:
2014.02.13
申请国别(地区):
AR
年份:
2015
代理人:
摘要:
Claim 1: a composition for oral administration comprising: 0.5 - 3.5% p High methoxy Pectin content, P 40 - 70% 16 - 30% glycerol, p 0 - 2, Water,At least 5% p of a Surfactant, 1.5 - 40% p at least another ingredient selected from the group consisting of: Sugar substitutes, FLAVORING agents,Colouring agents and / or active substances, percentages by weight relative to the total weight of the composition.Being understood and the PH of the composition in the range of (approximately) approximately 2.8 to 3.2.Claim 5: a Pharmaceutical composition comprising the composition of any of claims 1 to 4, which comprises at least one active substance,The active substance a substance Drug, optionally with a Pharmaceutical excipient.Claim 7: a process for preparing a Composition of any of claims 1 to 4, or a Pharmaceutical Composition of any of Claims 5 or 6That includes the following steps: Mixing glycerol (vii), Water (S), optionally with the active substance (S) and / or the surfactant (S), (viii) after heatingAdd High methoxy Pectin content, (IX) add the Sugar SUBSTITUTE (S), Agent (S) (S) and / or FLAVORING Agent (S), Colorant (S)If there is (X) heating the resulting mixture from step (ii) at a temperature of 140 degrees to 90 u00baC (XI), Adjust pH with acid(XII) the composition form and cool until gelation.Reivindicación 1: Una composición para administración oral, que comprende: 0,5 - 3,5 %p de pectina de alto contenido en metoxi, 40 - 70 %p de glicerol, 16 - 30 %p de agua, 0 - 2,5 %p de al menos un tensioactivo, 1,5 - 40 %p de al menos otros ingrediente seleccionado del grupo que consiste en: sustitutos del azúcar, agentes saborizantes, agentes colorantes y/o sustancias activas, siendo los porcentajes en peso relativos al peso total de la composición, y estando comprendido el pH de la composición dentro del intervalo de (aproximadamente) 2,8 a aproximadamente 3,2. Reivindicación 5: Una composición farmacéutica que comprende la composición de una cualquiera de las reiv
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