T. G. Murali Dhar,Jingwu Duan,Hua Gong,Bin Jiang,Zhonghui Lu,David S. Weinstein
申请号：
US15022673
公开号：
US09725443B2
申请日:
2014.09.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Described are RORγ modulators of the formula (I), or pharmaceutically acceptable salts thereof, wherein all substituents are defined herein. The invention includes stereoisomeric forms of the compounds of formula I, including stereoisomerically-pure, scalemic and racemic form, as well as tautomers thereof. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.
