The disclosure generally relates to the detection of symmetrical dimethylarginine (SDMA). More particularly, the disclosure relates to the detection of SDMA using a solid phase. The disclosure provides devices, reagents, kits and methods for detecting symmetrical dimethyl arginine (SDMA) in sample, such as a biological sample from an animal. The method includes detecting the presence or amount of SDMA in the sample by using an immunoassay format, such as a competitive immunoassay. The assay includes the use of antibodies to SDMA that are specific for SDMA and that have less affinity for other arginine derivatives.本揭示案大體關於對稱性二甲基精胺酸(SDMA)之檢測。更特定而言,本揭示案係關於使用固相檢測SDMA。本揭示案提供用於檢測諸如來自動物之生物樣本的樣本中對稱性二甲基精胺酸(SDMA)之裝置、試劑、套組及方法。該方法包括藉由使用諸如競爭性免疫分析之免疫分析形式檢測該樣本中SDMA之存在或量。該分析包括使用針對SDMA之抗體,其對SDMA具有特異性,且其針對其他精胺酸衍生物具有較低親和力。