I.C.G.E.B. International Centre for Genetic Engineering and Biotechnology
发明人:
GIACCA, Mauro,ZACCHIGNA, Serena,CUNHA MANO, Miguel Luis,BREGIEIRO EULALIO, Ana Sofia
申请号：
ES12823043
公开号：
ES2644574T3
申请日:
2012.12.21
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
The present invention discloses a set of human microRNAs, or a primary transcript for such microRNAs, or a precursor of such microRNAs, or a mimic of such microRNAs or a combination thereof, and their use as medicaments for inducing proliferation of cardiomyocytes for the prevention and treatment of heart diseases associated with a loss of cardiomyocytes. The invention also relates to a method for screening microRNAs and biological and therapeutically active compounds for their ability to increase proliferation of cardiomyocytes.
