Qing SHENG,Rakesh K. JAIN,Vasileios ASKOXYLAKIS,Gino B. FERRARO,Dai FUKUMURA,David P. KODACK
申请号：
US15535405
公开号：
US20190211110A1
申请日:
2015.12.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a pharmaceutical combination which comprises (a) a phosphatidylinositol 3-kinase inhibitor or pharmaceutically acceptable salt thereof, and (b) a Her3 antagonist, for simultaneous, separate or sequential administration for the treatment of breast cancer brain metastases； a method of treating a subject having a breast cancer brain metastases comprising administration of said combination to a subject in need thereof； use of such combination for the treatment of breast cancer brain metastases； and a commercial package comprising such combination.
