Dae Woong Jo,Jae Sun Ko,Jin Sook Kim,Kyung Mi Park,Jin Kyung Song,Jung Hee Lim,Thi Thuy Nga Do,Thi Lan Phuong Do,Minh Tam Duong
申请号:
US14091823
公开号:
US09040477B2
申请日:
2013.11.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention discloses novel macromolecule transduction domain (MTD) peptides which facilitate the traverse of a biologically active molecule across the cell membrane. Also disclosed are polynucleotides encoding the MTD peptides, methods of identifying the MTD peptides; methods of genetically engineering a biologically active molecule to have cell permeability by using the MTD peptides, methods of importing a biologically active molecule into a cell by using the MTD peptides, and uses thereof.