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Organ protection in PSMA-targeted radionuclide therapy of prostate cancer
专利权人:
Inc.;Molecular Insight Pharmaceuticals
发明人:
Babich, John W.,Hillier, Shawn,Joyal, John
申请号:
AU2020200214
公开号:
AU2020200214A1
申请日:
2020.01.10
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020200214A120200206.pdf#####ABSTRACT A method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with a cancer includes administering to the patient an agent capable of competing for binding sites on a surface of the non-cancerous tissue, provided that the administration is carried out after a waiting period that follows administration of a compound including a radionuclide to the patient, the compound having affinity for both a cancerous tissue and the non-cancerous tissue, and, further provided that the binding sites have an affinity for both the agent and the compound.1/6 [1251]MIP1095 PMPA CLEARANCEb 16h ~h 20hb22h 46-8h 16h 1h20h 22h 46-48h CONTROL: ~ 0.2mg/kg: I 4 ? I1mg/kg I10mg/kg: 4 h L 50mg/kg: FIG.I
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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