A sensor arrangement 100 for detecting information indicative of a physiological substance in a body material 102 of a physiological subject 106, wherein the sensor arrangement comprises a substrate 104, a first sensor structure 202 connected to the substrate and being configured for sensing the physiological substance electrochemically, and a second sensor structure 204 connected to the substrate and being configured for sensing the physiological substance by a luminescence detection. Embodiments include the use of phosphorescence or fluorescent detection as the luminescence detection. The physiological substance can be glucose. The system can be arranged as part of a catheter.
