Subhra Mohapatra,Shyam S. Mohapatra,Mark Howell,Rajesh Nair
申请号:
US15904176
公开号:
US20180256579A1
申请日:
2018.02.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are compositions and methods for treating cancer. Further provided herein are compositions and methods for reducing, inhibiting, or preventing resistance of cancer to tyrosine kinase inhibitors. The methods may include administering an anti-resistance agent such as a CYP51A1 inhibitor or an agonist of miRNA-764 (SEQ ID NO: 4) to a subject. A tyrosine kinase inhibitor may also be administered to the subject in addition to the anti-resistance agent.