Kyungpook National University Industry—Academic Cooperation Foundation
发明人:
Kiweon Cha,In-Seop So,Soyoun Kim,Byung-Heon Lee,In San Kim
申请号：
US14057654
公开号：
US08975369B2
申请日:
2013.10.18
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a novel protein skeletal module which increases the binding affinity or binding specificity of active polypeptides. More particularly, the present invention relates to a protein skeletal module comprising polypeptides consisting of the 1st to 19th amino acids of the amino acid sequence expressed in sequence number 1； polypeptides comprising active polypeptides； and polypeptides consisting of the 29th to 86th amino acids of the amino acid sequence expressed in sequence number 1. The present invention also relates to a method for preparing the protein skeletal module. The protein skeletal module of the present invention increases the binding affinity or binding specificity of active polypeptides embedded therein, and therefore is effective in diagnosing and treating diseases.
