GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
BRAVI, GIANPAOLO,HOBBS, HEATHER,INGLIS, GRAHAM GEORGE ADAM,NICOLLE, SIMON,PEACE, SIMON
申请号：
CA3085666
公开号：
CA3085666A1
申请日:
2018.12.12
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, L and A are as defined in the description and claims, or pharmaceutically acceptable salts thereof having mTOR kinase inhibitor activity. The invention also relates to pharmaceutical compositions including a compound of formula (I) or a pharmaceutically acceptable salt thereof, and to the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof in therapy, including in the treatment of a disease or condition for which an mTOR kinase inhibitor activity is indicated, and in particular the treatment of idiopathic pulmonary fibrosis.
