Compositions for treating alcohol hangover and methods of their use in treating or preventing hangover are described. The compositions include glycerophospholipids. Methods of use include administration or ingestion of the compositions after an episode of alcohol consumption. The compositions can be effective at preventing, eliminating, or reducing alcohol hangover when taken following an episode of alcohol consumption. In some embodiments, the glycerophospholipids are ingested with water or aqueous preparation, and some embodiments include B vitamins or other adjuvants.
