isolated polypeptide； isolated nucleic acid； expression or replication vector； host cell； transgenic animal； method of producing said polypeptide by an avian cell； method for producing said polypeptide in an egg of a chicken； and method of treating a disorder in an individual in need thereof
The present invention provides a novel fusion polypeptide containing a catalytic portion of NPP1 fused to a targeting moiety, nucleic acids encoding the fusion polypeptide, a vector containing the nucleic acid integrated thereinto, a host cell transformed with the vector and pharmaceutical compositions comprising the fusion polypeptide.
