HEYES, James,PALMER, Lorne R.,REID, Stephen P.,YAWORSKI, Edward D.,MACLACHLAN, Ian,WOOD, Mark,MARTIN, Alan D.
申请号：
EP14829948
公开号：
EP3033325A4
申请日:
2014.07.22
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention provides compositions comprising mRNA molecules encapsulated within lipid particles. The lipid particles comprise a cationic lipid, a non-cationic lipid, and an mRNA molecule that is encapsulated within the lipid particle. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease. The invention also provides cationic lipids that are useful for preparing the compositions of the invention.
