Marc F. Verhagen,Dean G. Stathakis,Lance E. Steward
申请号:
US12669447
公开号:
US08486422B2
申请日:
2008.06.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The specification discloses modified Clostridial toxins comprising an exogenous Clostridial toxin di-chain loop protease cleavage site located within the di-chain loop region polynucleotide molecules encoding such modified Clostridial toxins method of producing such modified Clostridial toxins, method of activating such modified Clostridial toxins and methods of activating recombinantly-expressed Clostridial toxins.