GUOXIAN WU,JACK LIN,KATRINA CHAN,MARIKA NESPI,PRABHA N. IBRAHIM,TODD EWING,WAYNE SPEVAK,YING ZHANG
申请号：
BR112015014752
公开号：
BR112015014752A2
申请日:
2013.12.20
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Abstract compounds active on c-kit protein kinases or mutant c-kit protein kinases having any mutations are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of the c-kit protein kinases and \/ or mutant c-kit protein ki Nases._ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ summary invention patent: \"compounds and methods for modulation of kinase, and indications for this.\Active compounds in c-kit protein kinases or protein kinases c-kit mutants having any mutations are described, as well as preparing and using such compounds to treat diseases and conditions associated with aberrant activity of c-kit protein kinases and \/ or c-kit protein kinases mutant Es.abstract compounds active on c-kit protein kinases or mutant c-kit protein kinases having any mutations are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of the c-kit protein kinases and/or mutant c-kit protein kinases. ________________________________________________________________________ resumo patente de invenção: "compostos e métodos para modulação de cinase, e indicações para isto". compostos ativos em c-kit proteína cinases ou c-kit proteína cinases mutantes tendo quaisquer mutações são descritos, bem como de preparar e usar tais compostos para tratar doenças e condições associadas com atividade aberrante das c-kit proteína cinases e/ou c-kit proteína cinases mutantes.
