Jerry Evarts,Leena Patel,Jennifer A. Treiberg,Stephane Perreault,Arthur Yeung,Lafe J. Purvis, II,Musong Kim
申请号:
US14137978
公开号:
US09018221B2
申请日:
2013.12.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure provides phosphatidylinositol 3-kinase (PI3K) inhibitors of formula (I),or pharmaceutically acceptable salts thereof, in which R1, R2, n, R3, R4, R5 and R6 are as defined herein. These compounds are useful for treatment of conditions mediated by one or more PI3K isoforms, such as PI3Kδ. The present disclosure further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by one or more PI3K isoforms, such as PI3Kδ.