Provided herein are exemplary compositions, products, and capsules utilizing POA, EPA, blends of POA and EPA, total algal oil compositions, and/or( Start ) whole biomass compositions in methods of inhibiting in flammation including in cardiovascular disease, diabetes,obesity,,stroke, metabolic syndromes, dementia,Alzheimer"s disease, and/or cancer. The exemplary compositions, products, and capsules may be orally, topically,intravenously, and/or subcutaneously administered. The exemplary compositions herein may be used as feed, food,food supplements, beverages, beverage supplements, nutritional products, products for athletic performance, pharmaceutical products, and/or medical products for mammalian use, including humans.