Disclosed is a left atrial appendage closure device, comprising a closure plate (106) and an anchor plate (101) connected to the closure plate (106). The closure plate (106) is in a mesh structure and is internally provided with a flow resisting film (108). The distal end of the closure plate (106) is fixed by a tubular member (109). The tubular member (109) is provided with a plurality of support rods (102) with respect to the other end of the closure plate (106). The support rods (102) are emitted from the direction relative to the closure plate (106). The proximal end of the support rod (102b) spans from the center of the tubular member (109) to the opposite side. A plurality of the support rods (102) are arranged in a cross radial shape to form the anchor plate (101). An angle with a specific angle is formed between the proximal end of the support bar (102b) and the central axis of the tubular member (109). The closure device also comprises a modified flow resisting film, improves biocompatibility, has rapid endothelialization, and can reduce thrombosis. The left atrial appendage closure device has a good effect of blocking the thrombus outflow from the left atrial appendage, can be repositioned, and has a stable fixation and a good fatigue resistance.
