The invention relates generally to antibodies that bind CD71, activatable antibodies that specifically bind to CD71 and methods of making and using these anti-CD71 antibodies and anti-CD71 activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.本發明大抵關於結合CD71之抗體、專一性結合CD71之可活化之抗體及製造及使用該等抗CD71抗體及抗CD71可活化之抗體於各種治療、診斷及預防適應症之方法。