The present invention provides a lactic acid bacterium which is suitable for use in food, drink or medicine, and which can inhibit an increase in serum uric acid level. Various lactic acid bacteria were cultured in the presence of purines, and the consumption amount of the purin body and the production amount of the purin body lysate were measured to select a plurality of lactic acid bacteria having remarkable purine cleavage ability. The lactic acid bacteria determined to have a high purifying ability by the above selection were orally administered to rats raised with a purin-containing feed, and the general condition and serum uric acid level of the rats were measured to examine the influence of the lactic acid bacteria on the serum uric acid value Respectively. As a result, Lactobacillus gasseri OLL2922 was found to significantly inhibit the increase of serum uric acid level.음식품이나 의약품 용도에 적합하고, 혈중 요산치의 상승을 억제 가능한 유산균을 제공한다.푸린체(purines) 존재하에서 각종 유산균을 배양하고, 그 푸린체의 소비량 및 그 푸린체 분해물의 생산량을 측정하여, 푸린체 분해능이 현저한 복수의 유산균을 선발하였다. 상기 선발에 의해 푸린체 분해능이 높다고 판단된 유산균을, 푸린체 함유 사료로 사육한 랫트에 경구투여하고, 당해 랫트의 일반상태 및 혈청 요산치를 측정하여, 유산균 투여에 따른 혈청 요산치로의 영향을 검토하였다. 그 결과, 혈청 요산치의 상승을 유의하게 억제하는 유산균:Lactobacillus gasseri OLL2922를 발견하였다.
