The present invention relates to a solid oral extended release pharmaceutical dosage form comprising a cured extended release matrix formulation, the extended release matrix formulation comprising:- a therapeutically effective amount of morphine sulfate, and- polyethylene oxide.The invention further relates to a process of preparing the dosage form as well as to a method of treating pain by administering the dosage form本發明係關於一種包含固化之延續釋放基質調配物的固體口服延續釋放醫藥劑型,該延續釋放基質調配物包含:治療有效量之硫酸嗎啡,及聚氧化乙烯。本發明進一步關於一種製備該劑型之方法以及藉由投與該劑型來治療疼痛之方法。