The utility model discloses a kind of braking mechanism of wheelchair, the technical problem that solve avoids causing injured because forgetting locking brake, increases the safety of wheelchair.The tire that this utility model comprises wheelchair frame, is arranged on the big wheel of wheelchair frame both sides and is arranged on big wheel, the outside of described wheelchair frame both sides medicated cushion pole is respectively equipped with braking mechanism, described braking mechanism comprises and is separately positioned on connecting rod outside medicated cushion pole, the brake lever that is arranged on connecting rod lower end, is arranged on the arrestment mechanism of handrail on the handrail pole of upper end, wheelchair frame both sides and cylinder lever connecting rod and handrail, the outside of described medicated cushion pole is provided with the first rotating shaft of the axes normal of axis and medicated cushion pole, and the middle part of connecting rod is plugged in the first rotating shaft.Compared with prior art, adopting and arrange a braking mechanism again on wheelchair, realizing brake function by pressing down handrail, hand can be carried out locking to wheelchair when lower wheelchair for balancing health by user automatically on handrail.