Yat Sun Or,Yong He,Ruichao Shen,Xuechao Xing,Brett Granger,Bin Wang,Jun Ma,Jing He,Jiang Long,Guoqiang Wang
申请号：
US15597423
公开号：
US10138228B2
申请日:
2017.05.17
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides compounds of Formula I:and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
