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SKIN ADHESIVE PREPARATION COMPRISING STABILIZED DONEPEZIL
专利权人:
NITTO DENKO CORPORATION
发明人:
HANATANI, AKINORI,SEKIYA, JUNICHI,TERASHI, SACHIKO,NISHI, SUMIYO,WASHIRO, SATOKO,AKEMI, HITOSHI
申请号:
EP07832914
公开号:
EP2098233A4
申请日:
2007.11.30
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
[Object] A donepezil-containing adhesive preparation is provided whereby formation of donepezil-related substances in a pressure-sensitive adhesive layer is inhibited.[Solution] A stabilizer containing one or more species selected from the group consisting of ascorbic acid, a metal salt or an ester thereof, isoascorbic acid or a metal salt thereof, ethylenediamine tetraacetic acid or a metal salt thereof, cysteine, acetylcysteine, 2-mercaptobenzimidazole, 3(2)-t-butyl-4-hydroxyanisole, 2,6-di-t-butyl-4-methylphenol, tetrakis[3-(3,5-di-t-butyl-4-hydroxyphenyl)propionic acid]pentaerythritol, 3-mercapto-1,2-propanediol, tocopherol acetate, rutin, quercetin, hydroquinone, a metal salt of hydroxymethanesulfinic acid, a metal metabisulfite salt, a metal sulfite salt and a metal thiosulfate salt, is blended in a donepezil-containing pressure-sensitive adhesive layer provided on at least one side of a support.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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