Disclosed is a polypeptide comprising at least two of: a)a first polypeptide comprising a first amino acid sequence consisting of a fragment of SEQ ID NO: 1 comprising an amino acid sequence set forth in SEQ ID NO: 10 (D3), SEQ ID NO: 36 (D3 sub-fragment), SEQ ID NO: 51 (D3+D4H) or SEQ ID NO: 53 (D2+D3+D4H)； b)a second polypeptide comprising a second amino acid sequence consisting of a fragment of SEQ ID NO: 2 comprising an amino acid sequence set forth in SEQ ID NO: 14 (D3), SEQ ID NO: 38 (D3 sub-fragment), SEQ ID NO: 55 (D3+D4H) or SEQ ID NO: 57 (D2+D3+D4H)； c)a third polypeptide comprising a third amino acid sequence consisting of fragment of SEQ ID NO: 3 comprising an amino acid sequence set forth in SEQ ID NO: 18 (D3), SEQ ID NO: 40 (D3 sub-fragment), SEQ ID NO: 59 (D3+D4H) or SEQ ID NO: 61 (D2+D3+D4H)； d)a fourth polypeptide comprising a fourth amino acid sequence consisting of a fragment of SEQ ID NO: 4 comprising an amino acid sequence set forth in SEQ ID NO: 22 (D3), SEQ ID NO: 42 (D3 sub-fragment), SEQ ID NO: 63 (D3+D4H) or SEQ ID NO: 65 (D2+D3+D4H)； e)a fifth polypeptide comprising a fifth amino acid sequence consisting of a fragment of SEQ ID NO: 5 comprising an amino acid sequence set forth in SEQ ID NO: 26 (D3), SEQ ID NO: 44 (D3 sub-fragment), SEQ ID NO: 67 (D3+D4H) or SEQ ID NO: 69 (D2+D3+D4H)； f)a sixth polypeptide comprising a sixth amino acid sequence consisting of a fragment of SEQ ID NO: 6 comprising an amino acid sequence set forth in SEQ ID NO: 30 (D3), SEQ ID NO: 46 (D3 sub-fragment), SEQ ID NO: 71 (D3+D4H) or SEQ ID NO: 73 (D2+D3+D4H)； and g)a seventh polypeptide comprising a seventh amino acid sequence consisting of a fragment of SEQ ID NO: 7 comprising an amino acid sequence set forth in SEQ ID NO: 34 (D3), SEQ ID NO: 48 (D3 sub-fragment), SEQ ID NO: 75 (D3+D4H) or SEQID NO: 77 (D2+D3+D4H), wherein the sequences are as defined in the complete specification. Also disclosed is the use of said polypeptide in the manufacture of a medicament fo
